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Biomarker Identification May Lead to New Noninvasive Test for Colorectal Cancer Detection (Reed Elsevier plc)

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(Source: Reed Elsevier plc) Philadelphia, PA, June 7, 2013 The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera. This test detected 87% of all stages of colorectal cancer cases (sensitivity) without significant difference between early and advanced stages, while correctly identifying 95% of disease-free patients (specificity). The results are published in the July issue of The Journal of Molecular Diagnostics. According to the US Centers for Disease Control and Prevention, CRC is the second leading...

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